Glutathione S-transferase Mu 2

BE0001189ProteinHumansGSTM2

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. It is acted on by 6 drugs in DrugBank.

Gene name
GSTM2
UniProtKB entry
P28161Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
218 residues · 25,744 Da
Also known as
2.5.1.18 · GST class-mu 2 · GST4 · GSTM2-2

Resolves to

Protein
UniProtP28161UniProt nameGSTM2_HUMAN
Gene
HGNCHGNC:4634NCBI Gene2946GenBank183301GeneCardsGSTM2
Pharmacology
KEGGhsa:2946
Structure
PDB1HNAPDB1HNBPDB1HNC
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutathione S-transferase Mu 2, how selective are they, and which programs against it are still in active trials?

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