Serum amyloid P-component

BE0001213ProteinHumansAPCS

Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. It is acted on by 10 drugs in DrugBank.

Gene name
APCS
UniProtKB entry
P02743Swiss-Prot
Cellular location
Secreted
Residues / weight
223 residues · 25,387 Da
Also known as
9.5S alpha-1-glycoprotein · PTX2 · SAP

Resolves to

Protein
UniProtP02743UniProt nameSAMP_HUMAN
Gene
HGNCHGNC:584NCBI Gene325GenBank220068GeneCardsAPCS
Pharmacology
IUPHAR/GtoPdb2839KEGGhsa:325
Structure
PDB1GYKPDB1LGNPDB1SAC
Drugs

What you can answer from here — as of September 07, 2019

10DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Serum amyloid P-component, how selective are they, and which programs against it are still in active trials?

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