Genome polyprotein

BE0001261ProteinDENV-2

Capsid protein C Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. It is acted on by 2 drugs in DrugBank.

UniProtKB entry
P12823Swiss-Prot
Cellular location
Virion
Residues / weight
3,388 residues · 379,216 Da
Also known as
3.4.21.91 · NS1

Resolves to

Protein
UniProtP12823UniProt namePOLG_DEN2P
Gene
GenBank323655
Structure
PDB1L9KPDB1OANPDB1OK8
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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28GO termsFunction, process and component, as structured annotations
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14Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Genome polyprotein, how selective are they, and which programs against it are still in active trials?

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