Beta-lactamase OXA-10

BE0001274ProteinPseudomonas aeruginosaOXA-10

Hydrolyzes both carbenicillin and oxacillin. It is acted on by 5 drugs in DrugBank.

Gene name
OXA-10
UniProtKB entry
P14489Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
266 residues · 29,507 Da
Also known as
3.5.2.6 · Beta-lactamase PSE-2 · bla · oxa10 · pse2

Resolves to

Protein
UniProtP14489UniProt nameBLO10_PSEAI
Gene
GenBank1019897
Pharmacology
KEGGag:AAB60534
Structure
PDB1E3UPDB1E4DPDB1EWZ
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Beta-lactamase OXA-10, how selective are they, and which programs against it are still in active trials?

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