Acetyl-CoA acetyltransferase, cytosolic

BE0001317ProteinHumansACAT2

Involved in the biosynthetic pathway of cholesterol. It is acted on by 2 drugs in DrugBank.

Gene name
ACAT2
UniProtKB entry
Q9BWD1Swiss-Prot
Cellular location
Cytoplasm, cytosol
Residues / weight
397 residues · 41,351 Da
Also known as
2.3.1.9 · Acetyl-CoA transferase-like protein · ACTL · Cytosolic acetoacetyl-CoA thiolase

Resolves to

Protein
UniProtQ9BWD1UniProt nameTHIC_HUMAN
Gene
HGNCHGNC:94NCBI Gene39GenBank546901GeneCardsACAT2
Pharmacology
IUPHAR/GtoPdb2436KEGGhsa:39
Structure
PDB1WL4PDB1WL5
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
1Clinical trialTrials of drugs acting on it, by phase and status
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
16+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Acetyl-CoA acetyltransferase, cytosolic, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In