Ferrichrome outer membrane transporter/phage receptor

BE0001326ProteinEscherichia coli (strain K12)fhuA

Involved in the uptake of iron in complex with ferrichrome, a hydroxamate-type siderophore. It is acted on by 18 drugs in DrugBank.

Gene name
fhuA
UniProtKB entry
P06971Swiss-Prot
Cellular location
Cell outer membrane
Residues / weight
747 residues · 82,182 Da
Also known as
Ferric hydroxamate receptor · Ferric hydroxamate uptake · Ferrichrome-iron receptor · tonA

Resolves to

Protein
UniProtP06971UniProt nameFHUA_ECOLI
Gene
NCBI Gene944856GenBank2226438
Pharmacology
KEGGecj:JW0146
Structure
PDB1BY3PDB1BY5PDB1FCP
Drugs

What you can answer from here — as of May 03, 2025

18DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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41+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Ferrichrome outer membrane transporter/phage receptor, how selective are they, and which programs against it are still in active trials?

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