D-alanyl-D-alanine carboxypeptidase

BE0001349ProteinStreptomyces sp. (strain R61)

Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. It is acted on by 13 drugs in DrugBank.

UniProtKB entry
P15555Swiss-Prot
Cellular location
Secreted
Residues / weight
406 residues · 42,917 Da
Also known as
3.4.16.4 · DD-carboxypeptidase

Resolves to

Protein
UniProtP15555UniProt nameDAC_STRSR
Gene
GenBank515050
Structure
PDB1CEFPDB1CEGPDB1HVB
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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33+ReferencesStructured and connected to the statements they support
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Which approved drugs act on D-alanyl-D-alanine carboxypeptidase, how selective are they, and which programs against it are still in active trials?

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