Galectin-3

BE0001353ProteinHumansLGALS3

Galactose-specific lectin which binds IgE. It is acted on by 8 drugs in DrugBank.

Gene name
LGALS3
UniProtKB entry
P17931Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
250 residues · 26,152 Da
Also known as
35 kDa lectin · Carbohydrate-binding protein 35 · CBP 35 · Gal-3 · Galactose-specific lectin 3

Resolves to

Protein
UniProtP17931UniProt nameLEG3_HUMAN
Gene
HGNCHGNC:6563NCBI Gene3958GenBank179531GeneCardsLGALS3
Pharmacology
KEGGhsa:3958
Structure
PDB1A3KPDB1KJLPDB1KJR
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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28GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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51+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Galectin-3, how selective are they, and which programs against it are still in active trials?

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