Bile salt hydrolase/transferase

BE0001392ProteinClostridium perfringens (strain 13 / Type A)cbh

Possesses dual functions in bile acid metabolism (PubMed:38326608). It is acted on by 4 drugs in DrugBank.

Gene name
cbh
UniProtKB entry
P54965Swiss-Prot
Residues / weight
329 residues · 37,185 Da
Also known as
3.5.1.24 · Bile acid amine N-acyltransferase · Bile salt hydrolase · BSH · BSH/T

Resolves to

Protein
UniProtP54965UniProt nameCBH_CLOPE
Gene
NCBI Gene988968GenBank882252
Pharmacology
KEGGcpe:CPE0709
Structure
PDB2BJFPDB2BJGPDB2RF8
Drugs

What you can answer from here — as of May 03, 2025

4DrugsApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Bile salt hydrolase/transferase, how selective are they, and which programs against it are still in active trials?

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