Tetanus toxin

BE0001411ProteinClostridium tetani (strain Massachusetts / E88)tetX

Tetanus toxin acts by inhibiting neurotransmitter release. It is acted on by 5 drugs in DrugBank.

Gene name
tetX
UniProtKB entry
P04958Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
1,315 residues · 150,681 Da
Also known as
3.4.24.68 · Tentoxylysin

Resolves to

Protein
UniProtP04958UniProt nameTETX_CLOTE
Gene
NCBI Gene24255210GenBank40770
Structure
PDB1A8DPDB1AF9PDB1D0H
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Tetanus toxin, how selective are they, and which programs against it are still in active trials?

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