Tetanus immune globulin is a solution of antibodies used to prevent tetanus after an injury. Tetanus Immune Globulin is manufactured from human plasma.
- Mechanism
- Curator reviewed · 1 reference
The immune globulin binds to tetanus toxiod, interfering with the normal interaction of the toxoid with human tissue. This prevents the toxoid from invading the nervous system and producing painful muscle spasms as well as autonomic dysfunction. The Clostridium tetani bacterium is killed either via antibiotic treatment of the host's immune system and immune globulin-bound toxoid is likely broken down by phagocytic immune cells.
- Primary indication
- For use as prophylaxis against tetanus in patients who are injured and have incomplete of uncertain immunization status.Curator reviewed · 2 structured indications
- First approval
- Canada, 2012 · United States, 1996
- Also known as
- Human clostridium tetani immune globulin · Human clostridium tetani toxoid immune globulin · Tetanus immune globulin human · Tetanus immune globulin,human · Tetanus immunoglobulin
- Brand names
Resolves to
What you can answer from here — as of September 10, 2025
Which drugs share a target with Tetanus immune globulin, and which of those have an active Phase 3 trial?
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