S-ribosylhomocysteine lyase

BE0001462ProteinDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)luxS

Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. It is acted on by 1 drug in DrugBank.

Gene name
luxS
UniProtKB entry
Q9RRU8Swiss-Prot
Residues / weight
158 residues · 17,395 Da
Also known as
4.4.1.21 · AI-2 synthesis protein · Autoinducer-2 production protein LuxS

Resolves to

Protein
UniProtQ9RRU8UniProt nameLUXS_DEIRA
Gene
NCBI Gene1797935GenBank6460202
Pharmacology
KEGGdra:DR_2387
Structure
PDB1INNPDB1J6VPDB1VGX
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on S-ribosylhomocysteine lyase, and which indications are they being tested in?

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