Pteridine reductase 1

BE0001467ProteinLeishmania majorPTR1

Exhibits a NADPH-dependent biopterin reductase activity. It is acted on by 4 drugs in DrugBank.

Gene name
PTR1
UniProtKB entry
Q01782Swiss-Prot
Residues / weight
288 residues · 30,456 Da
Also known as
1.5.1.33 · H region methotrexate resistance protein · HMTXR

Resolves to

Protein
UniProtQ01782UniProt namePTR1_LEIMA
Gene
NCBI Gene5651987GenBank13929426
Pharmacology
KEGGlma:LMJF_23_0270
Structure
PDB1E7WPDB1E92PDB1W0C
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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15+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Pteridine reductase 1, and which indications are they being tested in?

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