Isocitrate dehydrogenase [NADP]

BE0001524ProteinBacillus subtilis (strain 168)icd

Isocitrate dehydrogenase [NADP] (Bacillus subtilis (strain 168)) is a protein target in DrugBank. It is acted on by 4 drugs in DrugBank.

Gene name
icd
UniProtKB entry
P39126Swiss-Prot
Residues / weight
423 residues · 46,417 Da
Also known as
1.1.1.42 · citC · IDH · IDP · NADP(+)-specific ICDH

Resolves to

Protein
UniProtP39126UniProt nameIDH_BACSU
Gene
NCBI Gene938183GenBank487434
Pharmacology
KEGGbsu:BSU29130
Structure
PDB1HQS
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Isocitrate dehydrogenase [NADP], how selective are they, and which programs against it are still in active trials?

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