Endoglucanase G

BE0001539ProteinClostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)celCCG

The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose... It is acted on by 5 drugs in DrugBank.

Gene name
celCCG
UniProtKB entry
P37700Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
725 residues · 79,775 Da
Also known as
3.2.1.4 · Cellulase G · EGCCG · Endo-1,4-beta-glucanase G

Resolves to

Protein
UniProtP37700UniProt nameGUNG_RUMCH
Gene
GenBank551774
Pharmacology
KEGGcce:Ccel_0731
Structure
PDB1G87PDB1GA2PDB1K72
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
11+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Endoglucanase G, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In