Chloramphenicol acetyltransferase 3

BE0001542ProteinEscherichia colicat3

This enzyme is an effector of chloramphenicol resistance in bacteria. It is acted on by 3 drugs in DrugBank.

Gene name
cat3
UniProtKB entry
P00484Swiss-Prot
Residues / weight
213 residues · 24,993 Da
Also known as
2.3.1.28 · CAT-III · Chloramphenicol acetyltransferase III

Resolves to

Protein
UniProtP00484UniProt nameCAT3_ECOLX
Gene
GenBank47025
Pharmacology
KEGGag:CAA30695
Structure
PDB1CIAPDB1CLAPDB1QCA
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Chloramphenicol acetyltransferase 3, how selective are they, and which programs against it are still in active trials?

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