Phospholipase C

BE0001560ProteinBacillus cereusplc

Required, with sphingomyelinase, to effect target cell lysis (hemolysis). It is acted on by 4 drugs in DrugBank.

Gene name
plc
UniProtKB entry
P09598Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
283 residues · 32,383 Da
Also known as
3.1.4.3 · Cereolysin A · Phosphatidylcholine cholinephosphohydrolase · PLC

Resolves to

Protein
UniProtP09598UniProt namePHLC_BACCE
Gene
GenBank312906
Structure
PDB1AH7PDB1P5XPDB1P6D
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Phospholipase C, and which indications are they being tested in?

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