Outer membrane porin F

BE0001570ProteinEscherichia coli (strain K12)ompF

Forms pores that allow passive diffusion of small molecules across the outer membrane. It is acted on by 5 drugs in DrugBank.

Gene name
ompF
UniProtKB entry
P02931Swiss-Prot
Cellular location
Cell outer membrane
Residues / weight
362 residues · 39,333 Da
Also known as
cmlB · coa · cry · Outer membrane protein 1A · Outer membrane protein B

Resolves to

Protein
UniProtP02931UniProt nameOMPF_ECOLI
Gene
NCBI Gene945554GenBank147010
Pharmacology
KEGGecj:JW0912
Structure
PDB1BT9PDB1GFMPDB1GFN
Drugs

What you can answer from here — as of May 03, 2025

5DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Outer membrane porin F, how selective are they, and which programs against it are still in active trials?

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