Dihydrofolate reductase

BE0001614ProteinLactobacillus caseifolA

Key enzyme in folate metabolism. It is acted on by 4 drugs in DrugBank.

Gene name
folA
UniProtKB entry
P00381Swiss-Prot
Residues / weight
163 residues · 18,439 Da
Also known as
1.5.1.3 · dhfR

Resolves to

Protein
UniProtP00381UniProt nameDYR_LACCA
Gene
GenBank149540
Structure
PDB1AO8PDB1BZFPDB1DIS
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Dihydrofolate reductase, and which indications are they being tested in?

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