Peptide deformylase 2

BE0001645ProteinGeobacillus stearothermophilusdef2

Removes the formyl group from the N-terminal Met of newly synthesized proteins. It is acted on by 1 drug in DrugBank.

Gene name
def2
UniProtKB entry
O31410Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
184 residues · 20,382 Da
Also known as
3.5.1.88 · PDF 2 · Polypeptide deformylase 2

Resolves to

Protein
UniProtO31410UniProt nameDEF2_GEOSE
Gene
GenBank2266414
Structure
PDB1LQY
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptide deformylase 2, and which indications are they being tested in?

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