Spermidine/spermine N(1)-acetyltransferase

BE0001716ProteinBacillus subtilis (strain 168)paiA

Involved in the protection against polyamine toxicity by regulating their concentration. It is acted on by 2 drugs in DrugBank.

Gene name
paiA
UniProtKB entry
P21340Swiss-Prot
Residues / weight
172 residues · 20,015 Da
Also known as
Protease synthase and sporulation negative regulatory protein PAI 1 · SAT · Spermidine N(1)-acetyltransferase · SSAT

Resolves to

Protein
UniProtP21340UniProt namePAIA_BACSU
Gene
NCBI Gene937204GenBank143284
Pharmacology
KEGGbsu:BSU32150
Structure
PDB1TIQ
Drugs

What you can answer from here — as of September 04, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Spermidine/spermine N(1)-acetyltransferase, and which indications are they being tested in?

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