Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

BE0001745ProteinHumansACADM

Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation (FAO), breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats... It is acted on by 6 drugs in DrugBank.

Gene name
ACADM
UniProtKB entry
P11310Swiss-Prot
Cellular location
Mitochondrion matrix
Residues / weight
421 residues · 46,588 Da
Also known as
1.3.8.7 · MCAD · MCADH · Medium chain acyl-CoA dehydrogenase

Resolves to

Protein
UniProtP11310UniProt nameACADM_HUMAN
Gene
HGNCHGNC:89NCBI Gene34GenBank187433GeneCardsACADM
Pharmacology
KEGGhsa:34
Structure
PDB1EGCPDB1EGDPDB1EGE
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
2Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
1Metabolic reactionDrug transformations it catalyses, substrate to product
Sign in
13GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
39+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Medium-chain specific acyl-CoA dehydrogenase, mitochondrial, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In