Soluble calcium-activated nucleotidase 1

BE0001746ProteinHumansCANT1

Calcium-dependent nucleotidase with a preference for ribonucleosides diphosphate UDP, GDP and IDP, while having very low activity towards ADP and CDP (PubMed:12234496, PubMed:15006348, PubMed:15248776, PubMed:16835225). It is acted on by 1 drug in DrugBank.

Gene name
CANT1
UniProtKB entry
Q8WVQ1Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
401 residues · 44,839 Da
Also known as
3.6.1.6 · Apyrase homolog · Putative MAPK-activating protein PM09 · Putative NF-kappa-B-activating protein 107 · SCAN-1

Resolves to

Protein
UniProtQ8WVQ1UniProt nameCANT1_HUMAN
Gene
HGNCHGNC:19721NCBI Gene124583GenBank22218108GeneCardsCANT1
Pharmacology
KEGGhsa:124583
Structure
PDB1S18PDB1S1DPDB2H2N
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Soluble calcium-activated nucleotidase 1, and which indications are they being tested in?

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