Glutamate mutase sigma subunit

BE0001771ProteinClostridium tetanomorphumglmS

Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). It is acted on by 1 drug in DrugBank.

Gene name
glmS
UniProtKB entry
Q05488Swiss-Prot
Residues / weight
137 residues · 14,748 Da
Also known as
5.4.99.1 · Glutamate mutase S chain · Glutamate mutase small subunit · Methylaspartate mutase · mutS

Resolves to

Protein
UniProtQ05488UniProt nameGMSS_CLOTT
Gene
GenBank49240
Structure
PDB1BE1PDB1FMFPDB1ID8
Drugs

What you can answer from here — as of September 04, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Glutamate mutase sigma subunit, and which indications are they being tested in?

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