Bifunctional protein PutA

BE0001787ProteinEscherichia coli (strain K12)putA

Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon. It is acted on by 3 drugs in DrugBank.

Gene name
putA
UniProtKB entry
P09546Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
1,320 residues · 143,814 Da
Also known as
poaA

Resolves to

Protein
UniProtP09546UniProt namePUTA_ECOLI
Gene
NCBI Gene945600GenBank468875
Pharmacology
KEGGecj:JW0999
Structure
PDB1TIWPDB1TJ0PDB1TJ1
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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13GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Bifunctional protein PutA, how selective are they, and which programs against it are still in active trials?

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