3-dehydroquinate dehydratase

BE0001819ProteinSalmonella typhiaroD

Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. It is acted on by 1 drug in DrugBank.

Gene name
aroD
UniProtKB entry
P24670Swiss-Prot
Residues / weight
252 residues · 27,649 Da
Also known as
3-dehydroquinase · 4.2.1.10 · DHQ1 · Type I dehydroquinase · Type I DHQase

Resolves to

Protein
UniProtP24670UniProt nameAROD_SALTI
Gene
NCBI Gene1248131GenBank47642
Pharmacology
KEGGstt:t1231
Structure
PDB1GQNPDB1L9WPDB1QFE
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 3-dehydroquinate dehydratase, and which indications are they being tested in?

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