mRNA-capping enzyme

BE0001820ProteinPBCV-1

mRNA capping. Transfers a GMP cap onto the end of mRNA that terminates with a 5'-diphosphate tail. It is acted on by 2 drugs in DrugBank.

UniProtKB entry
Q84424Swiss-Prot
Residues / weight
330 residues · 37,832 Da
Also known as
GTP--RNA guanylyltransferase · mRNA guanylyltransferase

Resolves to

Protein
UniProtQ84424UniProt nameMCE_PBCV1
Gene
NCBI Gene918242GenBank1131446
Pharmacology
KEGGvg:918242
Structure
PDB1CKMPDB1CKNPDB1CKO
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on mRNA-capping enzyme, and which indications are they being tested in?

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