Malate dehydrogenase
Details
- Name
- Malate dehydrogenase
- Kind
- protein
- Synonyms
- 1.1.1.37
- Gene Name
- mdh
- UniProtKB Entry
- Q9ZF99Swiss-Prot
- Organism
- Aquaspirillum arcticum
- NCBI Taxonomy ID
- 87645
- Amino acid sequence
>lcl|BSEQ0019199|Malate dehydrogenase MAKTPMRVAVTGAAGQICYSLLFRIANGDMLGKDQPVILQLLEIPNEKAQKALQGVMMEI DDCAFPLLAGMTAHADPMTAFKDADVALLVGARPRGPGMERKDLLEANAQIFTVQGKAID AVASRNIKVLVVGNPANTNAYIAMKSAPSLPAKNFTAMLRLDHNRALSQIAAKTGKPVSS IEKLFVWGNHSPTMYADYRYAQIDGASVKDMINDDAWNRDTFLPTVGKRGAAIIDARGVS SAASAANAAIDHIHDWVLGTAGKWTTMGIPSDGSYGIPEGVIFGFPVTTENGEYKIVQGL SIDAFSQERINVTLNELLEEQNGVQHLLG
- Number of residues
- 329
- Molecular Weight
- 35251.11
- Theoretical pI
- 6.25
- GO Classification
- FunctionsL-malate dehydrogenase activityProcessescarbohydrate metabolic process / malate metabolic process / tricarboxylic acid cycle
- General Function
- Catalyzes the reversible oxidation of malate to oxaloacetate.
- Specific Function
- L-malate dehydrogenase activity
- Pfam Domain Function
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0003745|990 bp ATGGCTAAAACCCCAATGCGTGTTGCTGTTACCGGCGCCGCCGGTCAGATTTGCTACTCA CTGCTGTTTCGCATCGCCAACGGCGACATGCTCGGCAAGGATCAGCCAGTCATCTTGCAA CTGCTTGAAATCCCGAACGAAAAAGCCCAGAAGGCCCTGCAAGGCGTGATGATGGAAATC GACGATTGCGCCTTCCCTCTGCTGGCCGGCATGACCGCGCACGCTGATCCGATGACCGCA TTCAAGGATGCCGACGTCGCCTTGCTGGTCGGCGCGCGTCCACGCGGCCCCGGCATGGAG CGCAAGGATTTGCTGGAAGCCAATGCACAGATCTTCACGGTGCAAGGCAAGGCCATCGAT GCCGTCGCGTCGCGCAACATCAAGGTGCTCGTGGTCGGCAATCCGGCCAACACCAACGCC TATATCGCGATGAAATCGGCGCCTTCGCTGCCGGCCAAGAATTTCACCGCAATGCTGCGC CTGGATCACAACCGCGCCTTGTCGCAAATTGCTGCCAAGACCGGCAAACCGGTATCGTCG ATCGAAAAACTGTTCGTCTGGGGCAATCACTCGCCAACGATGTATGCCGACTACCGCTAC GCGCAAATCGACGGCGCATCGGTCAAGGACATGATCAATGACGACGCATGGAACCGCGAC ACGTTCTTGCCTACCGTGGGCAAGCGCGGCGCAGCCATCATCGATGCGCGCGGTGTATCG TCGGCTGCCTCGGCTGCCAATGCGGCCATCGATCACATCCATGACTGGGTGCTGGGCACG GCAGGCAAATGGACCACGATGGGCATCCCGTCCGATGGTTCGTATGGCATTCCGGAAGGG GTGATCTTCGGCTTCCCGGTCACGACCGAAAACGGCGAATACAAGATCGTCCAAGGCTTG AGCATTGACGCTTTCTCGCAAGAACGCATCAATGTCACACTGAACGAATTGCTGGAAGAG CAGAACGGCGTCCAGCATCTGCTGGGCTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9ZF99 UniProtKB Entry Name MDH_AQUAR GenBank Protein ID 4235484 GenBank Gene ID AF109682 PDB ID(s) 1B8P, 1B8U, 1B8V - General References
- Kim SY, Hwang KY, Kim SH, Sung HC, Han YS, Cho Y: Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum. J Biol Chem. 1999 Apr 23;274(17):11761-7. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Oxaloacetate Ion experimental unknown target Details