Esterase
Details
- Name
- Esterase
- Kind
- protein
- Synonyms
- 3.1.1.-
- Gene Name
- estA
- UniProtKB Entry
- P22266Swiss-Prot
- Organism
- Streptomyces scabiei
- NCBI Taxonomy ID
- 1930
- Amino acid sequence
>lcl|BSEQ0003758|Esterase MSSAMRKTTNSPVVRRLTAAAVALGSCLALAGPAGSAGAAPADPVPTVFFGDSYTANFGI APVTNQDSERGWCFQAKENYPAVATRSLADKGITLDVQADVSCGGALIHHFWEKQELPFG AGELPPQQDALKQDTQLTVGSLGGNTLGFNRILKQCSDELRKPSLLPGDPVDGDEPAAKC GEFFGTGDGKQWLDDQFERVGAELEELLDRIGYFAPDAKRVLVGYPRLVPEDTTKCLTAA PGQTQLPFADIPQDALPVLDQIQKRLNDAMKKAAADGGADFVDLYAGTGANTACDGADRG IGGLLEDSQLELLGTKIPWYAHPNDKGRDIQAKQVADKIEEILNR
- Number of residues
- 345
- Molecular Weight
- 36669.83
- Theoretical pI
- 4.46
- GO Classification
- Functionscarboxylic ester hydrolase activityComponentsextracellular region
- General Function
- Not Available
- Specific Function
- triglyceride lipase activity
- Pfam Domain Function
- Lipase_GDSL_2 (PF13472)
- Signal Regions
- 1-39
- Transmembrane Regions
- Not Available
- Cellular Location
- Secreted
- Gene sequence
>lcl|BSEQ0003757|1038 bp ATGTCTTCGGCCATGCGTAAGACGACGAATTCTCCGGTGGTACGGCGGCTGACCGCCGCG GCCGTCGCACTGGGCAGCTGCCTGGCGCTGGCCGGTCCGGCGGGAAGCGCGGGCGCGGCG CCCGCCGACCCCGTACCGACCGTCTTCTTCGGCGACTCCTACACCGCCAACTTCGGCATC GCTCCCGTGACCAACCAGGACAGCGAGAGGGGCTGGTGTTTCCAGGCGAAGGAGAACTAT CCCGCCGTCGCCACCCGGAGCCTGGCCGACAAGGGCATCACGCTCGACGTCCAGGCGGAC GTCTCCTGCGGAGGCGCGCTCATCCACCACTTCTGGGAGAAGCAGGAGCTGCCCTTCGGC GCCGGCGAGCTCCCGCCGCAGCAGGACGCGCTCAAGCAGGACACCCAGCTGACCGTGGGA AGCCTGGGCGGCAACACACTGGGTTTCAACCGCATCCTGAAGCAGTGTTCCGACGAGCTC CGGAAGCCCTCTCTGCTGCCGGGAGACCCGGTGGACGGGGACGAGCCGGCCGCCAAGTGC GGTGAGTTCTTCGGGACCGGGGACGGAAAGCAGTGGCTGGACGACCAGTTCGAGCGGGTC GGTGCGGAGCTGGAGGAGCTGCTCGACCGCATCGGCTACTTCGCCCCCGACGCCAAGCGC GTCCTGGTCGGCTACCCCCGGCTCGTGCCCGAGGACACCACCAAGTGCCTGACCGCGGCG CCCGGTCAGACGCAACTGCCGTTCGCCGACATCCCCCAGGACGCCCTGCCGGTCCTGGAC CAGATCCAGAAGCGGCTGAACGATGCCATGAAGAAGGCCGCCGCCGACGGCGGCGCCGAC TTCGTCGACCTCTACGCCGGCACCGGCGCCAACACGGCGTGCGACGGCGCCGACCGGGGC ATCGGCGGCCTGCTGGAGGACTCCCAGCTCGAACTCCTCGGCACCAAGATCCCCTGGTAC GCGCACCCCAATGACAAGGGCCGCGACATCCAGGCCAAGCAGGTGGCCGACAAGATCGAG GAGATCCTCAACCGGTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P22266 UniProtKB Entry Name ESTA_STRSC GenBank Protein ID 153255 GenBank Gene ID M57297 PDB ID(s) 1ESC, 1ESD, 1ESE - General References
- Raymer G, Willard JM, Schottel JL: Cloning, sequencing, and regulation of expression of an extracellular esterase gene from the plant pathogen Streptomyces scabies. J Bacteriol. 1990 Dec;172(12):7020-6. [Article]
- Schottel JL, Hale V, Babcock MJ: Regulation and secretion of an extracellular esterase from Streptomyces scabies. Gene. 1992 Jun 15;115(1-2):27-31. [Article]
- Wei Y, Schottel JL, Derewenda U, Swenson L, Patkar S, Derewenda ZS: A novel variant of the catalytic triad in the Streptomyces scabies esterase. Nat Struct Biol. 1995 Mar;2(3):218-23. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Methylphosphinic Acid experimental unknown target Details