Pseudoazurin

Details

Name
Pseudoazurin
Kind
protein
Synonyms
  • Blue copper protein
  • Cupredoxin
Gene Name
Not Available
UniProtKB Entry
P04377Swiss-Prot
Organism
Alcaligenes faecalis
NCBI Taxonomy ID
511
Amino acid sequence
>lcl|BSEQ0011407|Pseudoazurin
MRNIAIKFAAAGILAMLAAPALAENIEVHMLNKGAEGAMVFEPAYIKANPGDTVTFIPVD
KGHNVESIKDMIPEGAEKFKSKINENYVLTVTQPGAYLVKCTPHYAMGMIALIAVGDSPA
NLDQIVSAKKPKIVQERLEKVIASAK
Number of residues
146
Molecular Weight
15647.255
Theoretical pI
8.45
GO Classification
Functions
copper ion binding / electron carrier activity
Processes
oxidation-reduction process
Components
periplasmic space
General Function
This soluble electron transfer copper protein is required for the inactivation of copper-containing nitrite reductase in the presence of oxygen. Serves as a direct electron donor to the nitrite reductase.
Specific Function
copper ion binding
Pfam Domain Function
Signal Regions
1-23
Transmembrane Regions
Not Available
Cellular Location
Periplasm
Gene sequence
>lcl|BSEQ0003866|441 bp
ATGCGTAACATCGCGATCAAATTTGCTGCCGCAGGCATCCTCGCCATGCTGGCTGCCCCC
GCTCTTGCCGAAAATATCGAAGTTCATATGCTCAACAAGGGCGCCGAGGGCGCCATGGTT
TTCGAGCCTGCCTATATCAAGGCCAATCCCGGCGACACGGTCACCTTTATTCCGGTGGAC
AAAGGACATAATGTCGAATCCATCAAGGACATGATCCCTGAAGGCGCCGAAAAGTTCAAA
AGCAAGATCAACGAGAACTATGTGCTGACGGTTACCCAGCCCGGCGCATATCTGGTAAAG
TGCACACCGCATTATGCCATGGGTATGATCGCGCTCATCGCTGTCGGTGACAGCCCGGCC
AATCTCGACCAGATCGTTTCGGCCAAGAAGCCGAAGATTGTTCAGGAGCGGCTGGAAAAG
GTCATCGCCAGCGCCAAATAA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP04377
UniProtKB Entry NameAZUP_ALCFA
GenBank Protein ID141904
GenBank Gene IDM18267
PDB ID(s)1PAZ, 1PY0, 1PZA, 1PZB, 1PZC, 2P80, 3NYK, 3PAZ, 4PAZ, 4RH4, 5PAZ, 6PAZ, 7PAZ, 8PAZ
General References
  1. Yamamoto K, Uozumi T, Beppu T: The blue copper protein gene of Alcaligenes faecalis S-6 directs secretion of blue copper protein from Escherichia coli cells. J Bacteriol. 1987 Dec;169(12):5648-52. [Article]
  2. Hormel S, Adman E, Walsh KA, Beppu T, Titani K: The amino acid sequence of the blue copper protein of Alcaligenes faecalis. FEBS Lett. 1986 Mar 3;197(1-2):301-4. [Article]
  3. Petratos K, Banner DW, Beppu T, Wilson KS, Tsernoglou D: The crystal structure of pseudoazurin from Alcaligenes faecalis S-6 determined at 2.9 A resolution. FEBS Lett. 1987 Jun 29;218(2):209-14. [Article]
  4. Adman ET, Turley S, Bramson R, Petratos K, Banner D, Tsernoglou D, Beppu T, Watanabe H: A 2.0-A structure of the blue copper protein (cupredoxin) from Alcaligenes faecalis S-6. J Biol Chem. 1989 Jan 5;264(1):87-99. [Article]

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
7,10,13-Tri(Carboxymethyl)-5,15-Dioxo-4,7,10,13,16-Pentaaza-1,19-DithianonadecaneexperimentalunknowntargetDetails