Thermonuclease

BE0001977ProteinStaphylococcus aureusnuc

Enzyme that catalyzes the hydrolysis of both DNA and RNA at the 5' position of the phosphodiester bond. It is acted on by 2 drugs in DrugBank.

Gene name
nuc
UniProtKB entry
P00644Swiss-Prot
Cellular location
Secreted
Residues / weight
231 residues · 25,471 Da
Also known as
3.1.31.1 · Micrococcal nuclease · Staphylococcal nuclease · TNase

Resolves to

Protein
UniProtP00644UniProt nameNUC_STAAU
Gene
GenBank673492
Structure
PDB1A2TPDB1A2UPDB1A3T
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Thermonuclease, and which indications are they being tested in?

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