Endolysin

BE0001993ProteinEnterobacteria phage lambdaR

Endolysin with transglycosylase activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. It is acted on by 1 drug in DrugBank.

Gene name
R
UniProtKB entry
P03706Swiss-Prot
Cellular location
Host cytoplasm
Residues / weight
158 residues · 17,825 Da
Also known as
4.2.2.n2 · Lysis protein · Lysozyme · Muramidase · Transglycosylase

Resolves to

Protein
UniProtP03706UniProt nameENLYS_LAMBD
Gene
NCBI Gene2703480GenBank215163
Pharmacology
KEGGvg:2703480
Structure
PDB1AM7PDB1D9UPDB3D3D
Drugs

What you can answer from here — as of September 04, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Endolysin, and which indications are they being tested in?

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