Fibrinogen gamma chain

BE0002092ProteinHumansFGG

Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. It is acted on by 4 drugs in DrugBank.

Gene name
FGG
UniProtKB entry
P02679Swiss-Prot
Cellular location
Secreted
Residues / weight
453 residues · 51,511 Da

Resolves to

Protein
UniProtP02679UniProt nameFIBG_HUMAN
Gene
HGNCHGNC:3694NCBI Gene2266GenBank182439GeneCardsFGG
Pharmacology
KEGGhsa:2266
Structure
PDB1DUGPDB1FIBPDB1FIC
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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28GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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69+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Fibrinogen gamma chain, how selective are they, and which programs against it are still in active trials?

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