Complement C1q subcomponent subunit A

BE0002094ProteinHumansC1QA

Core component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens... It is acted on by 4 drugs in DrugBank.

Gene name
C1QA
UniProtKB entry
P02745Swiss-Prot
Cellular location
Secreted
Residues / weight
245 residues · 26,016 Da

Resolves to

Protein
UniProtP02745UniProt nameC1QA_HUMAN
Gene
HGNCHGNC:1241NCBI Gene712GenBank4894854GeneCardsC1QA
Pharmacology
KEGGhsa:712
Structure
PDB1PK6PDB2JG8PDB2JG9
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Complement C1q subcomponent subunit A, how selective are they, and which programs against it are still in active trials?

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