Actin, alpha skeletal muscle

BE0002101ProteinHumansACTA1

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. It is acted on by 13 drugs in DrugBank.

Gene name
ACTA1
UniProtKB entry
P68133Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
377 residues · 42,051 Da
Also known as
3.6.4.- · ACTA · Alpha-actin-1

Resolves to

Protein
UniProtP68133UniProt nameACTS_HUMAN
Gene
HGNCHGNC:129NCBI Gene58GenBank178029GeneCardsACTA1
Pharmacology
KEGGhsa:58
Structure
PDB7RNSPDB7RNUPDB7RNV
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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20GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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37+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Actin, alpha skeletal muscle, how selective are they, and which programs against it are still in active trials?

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