Latrunculin A

DB02621InvestigationalSmall molecule

Latrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer. It disrupts actin polymerization, prevents mitotic...

Formula / weight: C₂₂H₃₁NO₅S · 421.55 g/mol (avg)
Also known as: LAT-A · LatA
Code names: NSC-613011

Resolves to

Compound

UNIISRQ9WWM084CAS76343-93-6ChEMBLCHEMBL404116ChEBI69136PubChem445420

Structure

InChIKeyDDVBPZROPPMBLW-IZGXTMSKSA-NSMILES[H][C@]1(CSC(=O)N1)[C@@]1(O)C[C@H]2C[C@@H](CC[C@H](C)\C=C/C=C/CC\C(C)=C/C(=O)O2)O1

Targets

P68133ACTA1P06396GSNQ46220Iota toxin component Ia

What you can answer from here — as of September 23, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Latrunculin A, and which of those have an active Phase 3 trial?

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