Alanine aminotransferase 2

BE0002166ProteinHumansGPT2

Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. It is acted on by 4 drugs in DrugBank.

Gene name
GPT2
UniProtKB entry
Q8TD30Swiss-Prot
Residues / weight
523 residues · 57,903 Da
Also known as
2.6.1.2 · AAT2 · ALT2 · Glutamate pyruvate transaminase 2 · Glutamic--alanine transaminase 2

Resolves to

Protein
UniProtQ8TD30UniProt nameALAT2_HUMAN
Gene
HGNCHGNC:18062NCBI Gene84706GenBank19046894GeneCardsGPT2
Pharmacology
KEGGhsa:84706
Structure
PDB3IHJ
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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5GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Alanine aminotransferase 2, how selective are they, and which programs against it are still in active trials?

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