Glutathione S-transferase A2

BE0002189ProteinHumansGSTA2

Catalyzes the conjugation of glutathione to a large variety of electrophilic compounds. It is acted on by 9 drugs in DrugBank.

Gene name
GSTA2
UniProtKB entry
P09210Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
222 residues · 25,664 Da
Also known as
2.5.1.18 · GST class-alpha member 2 · GST HA subunit 2 · GST-gamma · GST2

Resolves to

Protein
UniProtP09210UniProt nameGSTA2_HUMAN
Gene
HGNCHGNC:4627NCBI Gene2939GenBank306811GeneCardsGSTA2
Pharmacology
KEGGhsa:2939
Structure
PDB1AGSPDB2VCTPDB2WJU
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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33+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutathione S-transferase A2, how selective are they, and which programs against it are still in active trials?

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