Thymidine phosphorylase

BE0002193ProteinHumansTYMP

May have a role in maintaining the integrity of the blood vessels. It is acted on by 13 drugs in DrugBank.

Gene name
TYMP
UniProtKB entry
P19971Swiss-Prot
Residues / weight
482 residues · 49,955 Da
Also known as
2.4.2.4 · ECGF1 · Gliostatin · PD-ECGF · Platelet-derived endothelial cell growth factor

Resolves to

Protein
UniProtP19971UniProt nameTYPH_HUMAN
Gene
HGNCHGNC:3148NCBI Gene1890GenBank189701GeneCardsTYMP
Pharmacology
KEGGhsa:1890
Structure
PDB1UOUPDB2J0FPDB2WK5
Drugs

What you can answer from here — as of September 07, 2019

13DrugsApproved to experimental, with action, bond type and pharmacological action
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18Clinical trialsTrials of drugs acting on it, by phase and status
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4Metabolic reactionsDrug transformations it catalyses, substrate to product
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3GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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52+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Thymidine phosphorylase, how selective are they, and which programs against it are still in active trials?

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