Substance-K receptor

BE0002222ProteinHumansTACR2

This is a receptor for the tachykinin neuropeptide substance K (neurokinin A) (PubMed:1659297, PubMed:1848773). It is acted on by 6 drugs in DrugBank.

Gene name
TACR2
UniProtKB entry
P21452Swiss-Prot
Cellular location
Cell membrane
Residues / weight
398 residues · 44,442 Da
Also known as
Neurokinin A receptor · NK-2 receptor · NK-2R · NK2R · NKNAR

Resolves to

Protein
UniProtP21452UniProt nameNK2R_HUMAN
Gene
HGNCHGNC:11527NCBI Gene6865GenBank189135GeneCardsTACR2
Pharmacology
IUPHAR/GtoPdb361KEGGhsa:6865
Structure
PDB7XWO
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Substance-K receptor, and which indications are they being tested in?

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