Voltage-dependent L-type calcium channel subunit alpha-1F

BE0002357ProteinHumansCACNA1F

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell... It is acted on by 6 drugs in DrugBank.

Gene name
CACNA1F
UniProtKB entry
O60840Swiss-Prot
Cellular location
Membrane
Residues / weight
1,977 residues · 220,676 Da
Also known as
CACNAF1 · Voltage-gated calcium channel subunit alpha Cav1.4

Resolves to

Protein
UniProtO60840UniProt nameCAC1F_HUMAN
Gene
HGNCHGNC:1393NCBI Gene778GenBank3183953GeneCardsCACNA1F
Pharmacology
IUPHAR/GtoPdb531KEGGhsa:778
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Voltage-dependent L-type calcium channel subunit alpha-1F, how selective are they, and which programs against it are still in active trials?

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