Protein kinase C delta type

BE0002417ProteinHumansPRKCD

Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine... It is acted on by 5 drugs in DrugBank.

Gene name
PRKCD
UniProtKB entry
Q05655Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
676 residues · 77,504 Da
Also known as
2.7.11.13 · nPKC-delta · PKCD · Tyrosine-protein kinase PRKCD

Resolves to

Protein
UniProtQ05655UniProt nameKPCD_HUMAN
Gene
HGNCHGNC:9399NCBI Gene5580GeneCardsPRKCD
Pharmacology
IUPHAR/GtoPdb1485KEGGhsa:5580
Structure
PDB1YRKPDB2YUU
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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46GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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45+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein kinase C delta type, how selective are they, and which programs against it are still in active trials?

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