Keratin, type II cytoskeletal 7

BE0002459ProteinHumansKRT7

Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. It is acted on by 2 drugs in DrugBank.

Gene name
KRT7
UniProtKB entry
P08729Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
469 residues · 51,385 Da
Also known as
CK-7 · Cytokeratin-7 · K7 · Keratin-7 · Sarcolectin

Resolves to

Protein
UniProtP08729UniProt nameK2C7_HUMAN
Gene
HGNCHGNC:6445NCBI Gene3855GeneCardsKRT7
Pharmacology
KEGGhsa:3855
Structure
PDB4XIF
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Keratin, type II cytoskeletal 7, how selective are they, and which programs against it are still in active trials?

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