Cytohesin-2

BE0002654ProteinHumansCYTH2

Acts as a guanine-nucleotide exchange factor (GEF). It is acted on by 5 drugs in DrugBank.

Gene name
CYTH2
UniProtKB entry
Q99418Swiss-Prot
Cellular location
Cell membrane
Residues / weight
400 residues · 46,546 Da
Also known as
ARF exchange factor · ARF nucleotide-binding site opener · ARNO · PH, SEC7 and coiled-coil domain-containing protein 2 · Protein ARNO

Resolves to

Protein
UniProtQ99418UniProt nameCYH2_HUMAN
Gene
HGNCHGNC:9502NCBI Gene9266GeneCardsCYTH2
Pharmacology
KEGGhsa:9266
Structure
PDB1PBVPDB1R8MPDB1R8Q
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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13+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cytohesin-2, how selective are they, and which programs against it are still in active trials?

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