Brefeldin A

DB07348ExperimentalSmall molecule

A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.

Chemical structure of Brefeldin A
Formula / weight
C16H24O4 · 280.3594 g/mol (avg)
Also known as
Ascotoxin · Cyanein · Decumbin · Nectrolide · Synergisidin
Code names
NSC-107456 · NSC-244390 · NSC-56310 · NSC-89671

Resolves to

Compound
UNIIXG0D35F9K6CAS20350-15-6ChEMBLCHEMBL19980ChEBI48080PubChem5287620
Structure
InChIKeyKQNZDYYTLMIZCT-KQPMLPITSA-NSMILES[H][C@]1(O)C[C@@]2([H])\C=C\CCC[C@]([H])(C)OC(=O)\C=C\[C@@]([H])(O)[C@]2([H])C1
Targets
Q99418CYTH2P84077ARF1

What you can answer from here — as of June 12, 2020

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
430Drug interactionsStructured to mechanism, not free text
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Brefeldin A, and which of those have an active Phase 3 trial?

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