Pyruvate:ferredoxin oxidoreductase

BE0002674ProteinDesulfovibrio africanuspor

Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate. It is acted on by 3 drugs in DrugBank.

Gene name
por
UniProtKB entry
P94692Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
1,232 residues · 133,679 Da
Also known as
1.2.7.1 · PFOR · POR · Pyruvate synthase · Pyruvate-ferredoxin oxidoreductase.

Resolves to

Protein
UniProtP94692UniProt namePFOR_DESAF
Structure
PDB1B0PPDB1KEKPDB2C3M
Drugs

What you can answer from here — as of May 03, 2025

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
6GO termsFunction, process and component, as structured annotations
Sign in
4Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
7+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Pyruvate:ferredoxin oxidoreductase, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In