6-oxocamphor hydrolase

BE0002845ProteinRhodococcus sp.camK

Catalyzes the carbon-carbon bond cleavage of the bicyclic beta-diketone 6-oxocamphor via a retro-Claisen reaction to yield the optically active (2R,4S)-beta-campholinic acid. It is acted on by 1 drug in DrugBank.

Gene name
camK
UniProtKB entry
Q93TU6Swiss-Prot
Residues / weight
257 residues · 28,483 Da
Also known as
3.7.1.18 · Beta-diketone hydrolase · OCH

Resolves to

Protein
UniProtQ93TU6UniProt nameCAMK_RHOSO
Pharmacology
KEGGag:AAK50622
Structure
PDB1O8UPDB1SZO
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 6-oxocamphor hydrolase, and which indications are they being tested in?

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