(S)-mandelate dehydrogenase

BE0003028ProteinPseudomonas putidamdlB

Catalyzes the dehydrogenation of (S)-mandelate to phenylglyoxylate (benzoylformate) (PubMed:10493804, PubMed:19465768). It is acted on by 5 drugs in DrugBank.

Gene name
mdlB
UniProtKB entry
P20932Swiss-Prot
Cellular location
Membrane
Residues / weight
393 residues · 43,437 Da
Also known as
1.1.99.31 · L(+)-mandelate dehydrogenase · MDH

Resolves to

Protein
UniProtP20932UniProt nameMDLB_PSEPU
Structure
PDB1HUVPDB1P4CPDB1P5B
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on (S)-mandelate dehydrogenase, how selective are they, and which programs against it are still in active trials?

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