Thiol peroxidase

BE0003067ProteinMycobacterium tuberculosistpx

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. It is acted on by 1 drug in DrugBank.

Gene name
tpx
UniProtKB entry
P9WG35Swiss-Prot
Residues / weight
165 residues · 16,896 Da
Also known as
1.11.1.- · 1.11.1.24 · Peroxiredoxin tpx · Probable thiol peroxidase · Prx

Resolves to

Protein
UniProtP9WG35UniProt nameTPX_MYCTU
Gene
NCBI Gene885357
Pharmacology
KEGGmtu:Rv1932
Structure
PDB1XVQPDB1Y25
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
13GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Thiol peroxidase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In