Proteinase inhibitor I4, serpin
Details
- Name
- Proteinase inhibitor I4, serpin
- Kind
- protein
- Synonyms
- Not Available
- Gene Name
- Not Available
- UniProtKB Entry
- Q47NK3TrEMBL
- Organism
- Thermobifida fusca (strain YX)
- NCBI Taxonomy ID
- 269800
- Amino acid sequence
>lcl|BSEQ0012199|Proteinase inhibitor I4, serpin MSGGFLRDDHLEFALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARATTRTELTTLL GTDPAPLLAALDRAVADSPDLASRTVLWVSADVPVRSSFRATVHDRPDSDVRTADFRTNP EGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWARARWTTPFEAHLTREGTF RTPRGPKRVPFMHRTGTMPYATARGWGMVTLHAHDELAVDVLLPPGTNAAAVPTAPLLTA LHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGISTVPLYVDTVIHQ ARLRVDERGAEGAAATAAMMLLAGAMPPRRTIRFSVDRPFHIVVRRRGAILFLGSIADPH DPGPAQ
- Number of residues
- 366
- Molecular Weight
- 39487.685
- Theoretical pI
- 8.56
- GO Classification
- Componentsextracellular space
- General Function
- Not Available
- Specific Function
- serine-type endopeptidase inhibitor activity
- Pfam Domain Function
- Serpin (PF00079)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0012200|Proteinase inhibitor I4, serpin ATGTCCGGCGGTTTCCTCCGTGATGACCACCTGGAGTTCGCGCTGCACCTGCACCGCAGG CTGGCCGAGGCTGTTCCTGACGGGGAGGTGATATGGTCGCCCTACTCCGTGGCCTGCGCC CTCGGCGTCCTCGCCGCGGGGGCGCGCGCCACCACCCGCACCGAATTGACCACGCTGCTC GGCACCGACCCTGCCCCGCTCCTCGCCGCGCTCGACCGCGCCGTCGCGGACAGCCCCGAC CTGGCGTCCCGCACCGTCCTGTGGGTGAGCGCAGACGTTCCCGTGCGCTCGTCCTTCCGC GCCACGGTGCACGACCGCCCCGATTCAGACGTGCGGACCGCGGACTTCCGCACCAACCCT GAAGGGGTCCGCGCCACCGTCAACGCGGACATCGCCGACGCTACCCGCGGGATGATCCGC GAACTGCTCCCGCAGGGAGCGGTCACCCCTGACCTGCGGGCGATTCTGACCAACGCCCTG TGGGCCAGGGCACGGTGGACCACCCCGTTCGAGGCGCACCTGACCCGGGAGGGGACGTTC CGCACCCCGCGCGGGCCGAAACGCGTCCCGTTCATGCACCGCACCGGGACGATGCCCTAC GCCACGGCGCGCGGCTGGGGAATGGTGACCCTGCACGCCCACGACGAACTCGCGGTCGAC GTCCTGCTGCCGCCGGGCACGAACGCCGCCGCTGTGCCGACCGCGCCGCTGCTCACCGCC TTGCACCGGCGTTCCGCATCCACCAGTGTCGAGCTGGCTCTCCCCCGCTTCGAACTGACC CAGCCGCACCAACTCGTCGAAGTCCTGGCTGAGGCGGGGGTACGCACGCTCTTCACCGCC TCCGCTGACCTGTCCGGGATCTCCACGGTGCCGCTCTACGTGGACACGGTCATCCACCAG GCCAGGCTCCGGGTGGATGAACGGGGCGCGGAAGGAGCGGCAGCGACCGCAGCCATGATG CTCCTGGCCGGTGCCATGCCGCCGCGGCGGACGATCCGGTTCAGCGTCGACCGGCCGTTC CACATCGTGGTACGCCGCCGCGGCGCCATCCTGTTCCTCGGGTCGATCGCCGACCCGCAC GACCCCGGTCCGGCCCAGTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q47NK3 UniProtKB Entry Name Q47NK3_THEFY GenBank Gene ID CP000088 PDB ID(s) 1MTP, 1SNG KEGG ID tfu:Tfu_1933 - General References
- Irving JA, Cabrita LD, Rossjohn J, Pike RN, Bottomley SP, Whisstock JC: The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment. Structure. 2003 Apr;11(4):387-97. [Article]
- Fulton KF, Buckle AM, Cabrita LD, Irving JA, Butcher RE, Smith I, Reeve S, Lesk AM, Bottomley SP, Rossjohn J, Whisstock JC: The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition. J Biol Chem. 2005 Mar 4;280(9):8435-42. Epub 2004 Dec 7. [Article]
- Lykidis A, Mavromatis K, Ivanova N, Anderson I, Land M, DiBartolo G, Martinez M, Lapidus A, Lucas S, Copeland A, Richardson P, Wilson DB, Kyrpides N: Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX. J Bacteriol. 2007 Mar;189(6):2477-86. Epub 2007 Jan 5. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Cystein-S-Yl Cacodylate experimental unknown target Details